Genomics & Systems Biology

(NYU Center for Genomics and Systems Biology)

We are in the midst of a new revolution in biology called genomics, which has as its goal the analysis of the complete genetic material of organisms. Genomics is a rapidly emerging field, in which subdisciplines are only beginning to be defined. The area of functional genomics attempts to determine the function of genes based on high-throughput approaches, starting from the complete genomic sequences of one or more species. Within functional genomics itself, the areas most intensively studied include RNA expression analysis, large-scale mutagenesis, and cross-species comparative analysis. NYU's Center for Genomics and Systems Biology uses all of these approaches with a focus on using evolutionary insights to address biological networks. Faculty affiliated with the Center sponsors seminars and offer courses in Genomics and Bioinformatics.

NYU Biology Faculty in this research area:
Ken Birnbaum Plant Genomics & Networks
Richard Bonneau (Biology/CS) Systems Biology and Protein Structure
Francesca Chiaromonte (Math/Biology) Statistical Genomics
Gloria Coruzzi Plant Genomics & Networks
Claude Desplan Fly Evolutionary Genomics
Patrick Eichenberger Microbial Genomics
David Fitch C. elegans Evolutionary Genomics
Kris Gunsalus Databases and Systems Biology
Edo Kussell Computational biology, evolution, and biological physics
Fabio Piano C. elegans Genomics & Networks
Michael Purugganan Plant Evolutionary Genomics
Mark Siegal Fly Genomics & Networks
Stephen Small Fly Transcription Networks
Rob DeSalle (AMNH) Evolutionary Genomics

Sample Course Curriculum for Ph.D. Program:

Biology CORE COURSES:
Bio Core 1: Molecules and Cells G23.1001
Bio Core 2: Genes, Systems and Evolution G23.1002
Bio Core 3: Molecules and Cells/Discussion-Based G23.2003
Bio Core 4: Genes, Systems and Evolution/Discussion-Based G23.2004
The Art of Scientific Investigation G23.3001
Statistics in Biology G23.2030

SPECIALIZED COURSES IN GENOMICS AND BIOINFORMATICS:
Bioinformatics and Genomes G23.1127 (Bonneau)
Genomics G23.1128 (Piano)
Statistical Analysis of Genomics Data (G63.2852.003/G23.2852.003) (Chiaromonte)
Diagnostic Genomics G23.XXXX (New for Spring 2007) (Siegal/Birnbaum)
Introduction to Biostatistics G23.2303

GENETICS OFFERINGS IN GENOMIC CONTEXT:
Principles of Evolution G23.1069
Molecular Controls of Organism Form and Function G23.1072
Advanced Genetics G23.1126
Developmental Genetics I G23.2130

Courant Offerings:
Fundamental Algorithms G22.1170
Programing Languages G22.2110
Database Systems G22.2433
Systems Biology G22.3033

For students who need more computer science background, it is advisable to take C-Pac I,G22.1133, and C-Pac II, G22.1144, and Unix Tools, G22.2245.